BDBM50042232 2-{4-[2-butyl-5-oxospiro[4,5-dihydro-1H-imidazole-4,2'-(2',3'-dihydro-1'H-indene)]-1-ylmethyl]phenyl}benzoic acid::CHEMBL114983

SMILES: CCCCC1=NC2(Cc3ccccc3C2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=YIXCSIBUXLSBBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50042232 (2-{4-[2-butyl-5-oxospiro[4,5-dihydro-1H-imidazole-...) Show SMILES CCCCC1=NC2(Cc3ccccc3C2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| Show InChI InChI=1S/C29H28N2O3/c1-2-3-12-26-30-29(17-22-8-4-5-9-23(22)18-29)28(34)31(26)19-20-13-15-21(16-14-20)24-10-6-7-11-25(24)27(32)33/h4-11,13-16H,2-3,12,17-19H2,1H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Recherche Curated by ChEMBL					Assay Description Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...				J Med Chem 36: 3371-80 (1993) BindingDB Entry DOI: 10.7270/Q22Z14M0
					More data for this Ligand-Target Pair