BDBM50042240 4'-(2-Butyl-4,4-diethyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL296883

SMILES: CCCCC1=NC(CC)(CC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=LCPYFBSBBAXCRH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50042240 (4'-(2-Butyl-4,4-diethyl-5-oxo-4,5-dihydro-imidazol...) Show SMILES CCCCC1=NC(CC)(CC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| Show InChI InChI=1S/C25H30N2O3/c1-4-7-12-22-26-25(5-2,6-3)24(30)27(22)17-18-13-15-19(16-14-18)20-10-8-9-11-21(20)23(28)29/h8-11,13-16H,4-7,12,17H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at Angiotensin II receptor, type 1 from rat liver membrane by [125I]- A II displacement.				Bioorg Med Chem Lett 4: 163-168 (1994) Article DOI: 10.1016/S0960-894X(01)81140-9 BindingDB Entry DOI: 10.7270/Q2M045CQ
					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50042240 (4'-(2-Butyl-4,4-diethyl-5-oxo-4,5-dihydro-imidazol...) Show SMILES CCCCC1=NC(CC)(CC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| Show InChI InChI=1S/C25H30N2O3/c1-4-7-12-22-26-25(5-2,6-3)24(30)27(22)17-18-13-15-19(16-14-18)20-10-8-9-11-21(20)23(28)29/h8-11,13-16H,4-7,12,17H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Recherche Curated by ChEMBL					Assay Description Binding affinity for Angiotensin II receptor, type 1 measured by ability to displace [125I]- A II from its specific binding site in rat liver membran...				J Med Chem 36: 3371-80 (1993) BindingDB Entry DOI: 10.7270/Q22Z14M0
					More data for this Ligand-Target Pair