BDBM50042461 CHEMBL3353279

SMILES: COc1cc(ccc1Cl)C12N(CCN1C(=O)c1ccccc21)C(=O)c1cc(F)c(F)c(F)c1

InChI Key: InChIKey=ZQAYPVBUJWQWIR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50042461 (CHEMBL3353279) Show SMILES COc1cc(ccc1Cl)C12N(CCN1C(=O)c1ccccc21)C(=O)c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C24H16ClF3N2O3/c1-33-20-12-14(6-7-17(20)25)24-16-5-3-2-4-15(16)23(32)30(24)9-8-29(24)22(31)13-10-18(26)21(28)19(27)11-13/h2-7,10-12H,8-9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Negative allosteric modulation of human muscarinic acetylcholine receptor M5 expressed in CHO cells assessed as inhibition of acetylcholine-induced c...				Bioorg Med Chem Lett 25: 690-4 (2015) Article DOI: 10.1016/j.bmcl.2014.11.082 BindingDB Entry DOI: 10.7270/Q2HD7X8T
					More data for this Ligand-Target Pair