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BDBM50042552 2-Benzyl-5-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid ethyl ester::CHEMBL120762

SMILES: CCCc1nn(Cc2ccccc2)c(C(=O)OCC)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=DQARLNOUQUUEOQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042552   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(RABBIT)		BDBM50042552
PNG
(2-Benzyl-5-propyl-4-[2'-(1H-tetrazol-5-yl)-bipheny...)
Show SMILES CCCc1nn(Cc2ccccc2)c(C(=O)OCC)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C30H30N6O2/c1-3-10-27-26(28(30(37)38-4-2)36(33-27)20-22-11-6-5-7-12-22)19-21-15-17-23(18-16-21)24-13-8-9-14-25(24)29-31-34-35-32-29/h5-9,11-18H,3-4,10,19-20H2,1-2H3,(H,31,32,34,35)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 22n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1

J Med Chem 36: 3595-605 (1994)


BindingDB Entry DOI: 10.7270/Q25Q4V5H
More data for this
Ligand-Target Pair