BDBM50042659 CHEMBL3353870::Example 190 in WO2010077836::US10570125, Example 190

SMILES: CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1

InChI Key: InChIKey=FWARWBPCFONFSB-ZDUSSCGKSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50042659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50042659 (CHEMBL3353870 | Example 190 in WO2010077836 | US10...) Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 |r| Show InChI InChI=1S/C17H27N3O3/c1-17(2,3)14-11-15(23-19-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,21)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins				Bioorg Med Chem Lett 25: 581-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.019 BindingDB Entry DOI: 10.7270/Q2CN75H1
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50042659 (CHEMBL3353870 | Example 190 in WO2010077836 | US10...) Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 |r| Show InChI InChI=1S/C17H27N3O3/c1-17(2,3)14-11-15(23-19-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,21)/t13-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins				Bioorg Med Chem Lett 25: 581-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.019 BindingDB Entry DOI: 10.7270/Q2CN75H1
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50042659 (CHEMBL3353870 | Example 190 in WO2010077836 | US10...) Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 |r| Show InChI InChI=1S/C17H27N3O3/c1-17(2,3)14-11-15(23-19-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,21)/t13-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	7.87E+3	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description CB1: CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37°...				US Patent US10570125 (2020) BindingDB Entry DOI: 10.7270/Q21C209H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50042659 (CHEMBL3353870 | Example 190 in WO2010077836 | US10...) Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 |r| Show InChI InChI=1S/C17H27N3O3/c1-17(2,3)14-11-15(23-19-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,21)/t13-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	438	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...				US Patent US10112934 (2018) BindingDB Entry DOI: 10.7270/Q2F191RP
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50042659 (CHEMBL3353870 | Example 190 in WO2010077836 | US10...) Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 |r| Show InChI InChI=1S/C17H27N3O3/c1-17(2,3)14-11-15(23-19-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,21)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description CB2: CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37°...				US Patent US10570125 (2020) BindingDB Entry DOI: 10.7270/Q21C209H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50042659 (CHEMBL3353870 | Example 190 in WO2010077836 | US10...) Show SMILES CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2C2CCOCC2)on1 |r| Show InChI InChI=1S/C17H27N3O3/c1-17(2,3)14-11-15(23-19-14)18-16(21)13-5-4-8-20(13)12-6-9-22-10-7-12/h11-13H,4-10H2,1-3H3,(H,18,21)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Centrexion Therapeutics Corporation US Patent					Assay Description CHO cells expressing human CB2R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...				US Patent US10112934 (2018) BindingDB Entry DOI: 10.7270/Q2F191RP
					More data for this Ligand-Target Pair