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BDBM50042717 12-(2-methyl-1H-1-imidazolylmethyl)-5,6,7,8,10,11,12,13-octahydro-4H-azocino[3,2,1-jk]carbazol-13-one::CHEMBL123643

SMILES: Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCCCCn2c13

InChI Key: InChIKey=RLXQUWKBZWYVNI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042717   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50042717
PNG
(12-(2-methyl-1H-1-imidazolylmethyl)-5,6,7,8,10,11,...)
Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCCCCn2c13
Show InChI InChI=1S/C22H25N3O/c1-15-23-11-13-24(15)14-17-9-10-19-20(22(17)26)18-8-5-7-16-6-3-2-4-12-25(19)21(16)18/h5,7-8,11,13,17H,2-4,6,9-10,12,14H2,1H3
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
 1.10n/an/an/an/an/an/an/an/a



Solvay Duphar B.V.

Curated by ChEMBL


Assay Description
The binding affinity of the compound was measured on 5-hydroxytryptamine 3 receptor using [3H]- GR-65,630 as radioligand.

J Med Chem 36: 3693-9 (1994)


BindingDB Entry DOI: 10.7270/Q2NS0SZH
More data for this
Ligand-Target Pair