BDBM50042880 CHEMBL3354523

SMILES: Fc1cccc(F)c1-c1nc(cs1)-c1ccc2nccc(N3CCNCC3)c2c1

InChI Key: InChIKey=HDECOLDRAJGUTB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50042880 (CHEMBL3354523) Show SMILES Fc1cccc(F)c1-c1nc(cs1)-c1ccc2nccc(N3CCNCC3)c2c1 Show InChI InChI=1S/C22H18F2N4S/c23-16-2-1-3-17(24)21(16)22-27-19(13-29-22)14-4-5-18-15(12-14)20(6-7-26-18)28-10-8-25-9-11-28/h1-7,12-13,25H,8-11H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				Bioorg Med Chem Lett 25: 474-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.041 BindingDB Entry DOI: 10.7270/Q2VQ34BW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50042880 (CHEMBL3354523) Show SMILES Fc1cccc(F)c1-c1nc(cs1)-c1ccc2nccc(N3CCNCC3)c2c1 Show InChI InChI=1S/C22H18F2N4S/c23-16-2-1-3-17(24)21(16)22-27-19(13-29-22)14-4-5-18-15(12-14)20(6-7-26-18)28-10-8-25-9-11-28/h1-7,12-13,25H,8-11H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin)				Bioorg Med Chem Lett 25: 474-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.041 BindingDB Entry DOI: 10.7270/Q2VQ34BW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50042880 (CHEMBL3354523) Show SMILES Fc1cccc(F)c1-c1nc(cs1)-c1ccc2nccc(N3CCNCC3)c2c1 Show InChI InChI=1S/C22H18F2N4S/c23-16-2-1-3-17(24)21(16)22-27-19(13-29-22)14-4-5-18-15(12-14)20(6-7-26-18)28-10-8-25-9-11-28/h1-7,12-13,25H,8-11H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin)				Bioorg Med Chem Lett 25: 474-80 (2015) Article DOI: 10.1016/j.bmcl.2014.12.041 BindingDB Entry DOI: 10.7270/Q2VQ34BW
					More data for this Ligand-Target Pair