BDBM50043214 8-(1-Phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::CHEMBL128804
SMILES: CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)[C@H](C)c1ccccc1
InChI Key: InChIKey=LVOKVZZFKWMOQE-CYBMUJFWSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50043214 (8-(1-Phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 25.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]-CHA in whole rat brain membranes at 25 degree C | J Med Chem 36: 4015-20 (1994) BindingDB Entry DOI: 10.7270/Q23T9G92 | |||||||||||
More data for this Ligand-Target Pair |