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SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)[C@@H](S)CC(=O)OC(C)(C)C

InChI Key: InChIKey=ABIWLTAZMOAKEU-AABGKKOBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043227   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interstitial collagenase


(Homo sapiens (Human))		BDBM50043227
PNG
(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)[C@@H](S)CC(=O)OC(C)(C)C
Show InChI InChI=1S/C24H38N2O5S/c1-15(2)12-18(20(32)14-21(27)31-24(3,4)5)22(28)26-19(23(29)25-6)13-16-8-10-17(30-7)11-9-16/h8-11,15,18-20,32H,12-14H2,1-7H3,(H,25,29)(H,26,28)/t18-,19+,20+/m1/s1
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MMDB

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Similars
PubMed
n/an/a 10n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.

J Med Chem 36: 4030-9 (1994)


BindingDB Entry DOI: 10.7270/Q2028QM3
More data for this
Ligand-Target Pair