BDBM50043255 2-Propyl-6-pyridin-2-yl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-benzoimidazole::CHEMBL132282

SMILES: CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccn1

InChI Key: InChIKey=PFYMSMASTADICJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50043255 (2-Propyl-6-pyridin-2-yl-1-[2'-(1H-tetrazol-5-yl)-b...) Show SMILES CCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccn1 Show InChI InChI=1S/C29H25N7/c1-2-7-28-31-26-16-15-22(25-10-5-6-17-30-25)18-27(26)36(28)19-20-11-13-21(14-12-20)23-8-3-4-9-24(23)29-32-34-35-33-29/h3-6,8-18H,2,7,19H2,1H3,(H,32,33,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparation				J Med Chem 36: 4040-51 (1994) BindingDB Entry DOI: 10.7270/Q2V98746
					More data for this Ligand-Target Pair