BDBM50043327 2-Hydroxy-5-(2-hydroxy-benzylamino)-benzoic acid methyl ester::CHEMBL132907

SMILES: COC(=O)c1cc(NCc2ccccc2O)ccc1O

InChI Key: InChIKey=GIAGGFBJOMQPDM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 4 (Homo sapiens (Human))	BDBM50043327 (2-Hydroxy-5-(2-hydroxy-benzylamino)-benzoic acid m...) Show SMILES COC(=O)c1cc(NCc2ccccc2O)ccc1O Show InChI InChI=1S/C15H15NO4/c1-20-15(19)12-8-11(6-7-14(12)18)16-9-10-4-2-3-5-13(10)17/h2-8,16-18H,9H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay				J Med Chem 53: 6758-62 (2010) Article DOI: 10.1021/jm1004368 BindingDB Entry DOI: 10.7270/Q2F18ZZ5
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50043327 (2-Hydroxy-5-(2-hydroxy-benzylamino)-benzoic acid m...) Show SMILES COC(=O)c1cc(NCc2ccccc2O)ccc1O Show InChI InChI=1S/C15H15NO4/c1-20-15(19)12-8-11(6-7-14(12)18)16-9-10-4-2-3-5-13(10)17/h2-8,16-18H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]-TdR				J Med Chem 36: 4094-8 (1994) BindingDB Entry DOI: 10.7270/Q2KS6QMV
					More data for this Ligand-Target Pair