BDBM50043333 CHEMBL3355053
SMILES: Fc1ccc(cc1)C(=O)Nc1ccc2CCNCc2c1
InChI Key: InChIKey=PGZJYUJKVGSJFI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Maternal embryonic leucine zipper kinase (MELK) (Homo sapiens (Human)) | BDBM50043333 (CHEMBL3355053) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astex Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of MELK kinase (unknown origin) using biotinylated ZIP-tide peptide/gamma[33P]ATP by scintillation counting analysis | ACS Med Chem Lett 6: 25-30 (2015) Article DOI: 10.1021/ml5001245 BindingDB Entry DOI: 10.7270/Q29P3388 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |