BDBM50043347 1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthracen-9-one::CHEMBL130382

SMILES: [#8]-c1cccc2\[#6](=[#6]/[#6]-[#6]-c3ccccc3)-c3cccc(-[#8])c3-[#6](=O)-c12

InChI Key: InChIKey=MTGASNJOVYOTIC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043347 (1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthra...) Show SMILES [#8]-c1cccc2\[#6](=[#6]/[#6]-[#6]-c3ccccc3)-c3cccc(-[#8])c3-[#6](=O)-c12 Show InChI InChI=1S/C23H18O3/c24-19-13-5-11-17-16(10-4-9-15-7-2-1-3-8-15)18-12-6-14-20(25)22(18)23(26)21(17)19/h1-3,5-8,10-14,24-25H,4,9H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043347 (1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthra...) Show SMILES [#8]-c1cccc2\[#6](=[#6]/[#6]-[#6]-c3ccccc3)-c3cccc(-[#8])c3-[#6](=O)-c12 Show InChI InChI=1S/C23H18O3/c24-19-13-5-11-17-16(10-4-9-15-7-2-1-3-8-15)18-12-6-14-20(25)22(18)23(26)21(17)19/h1-3,5-8,10-14,24-25H,4,9H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomes				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair