null

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1

InChI Key: InChIKey=YGTGXBGVWRJJFN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50043464 ((3,5-Bis-trifluoromethyl-phenyl)-[4-(2-ethyl-5,7-d...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C27H24F6N4O2/c1-4-21-36-22-14(2)9-15(3)34-24(22)37(21)13-16-5-7-20(8-6-16)35-23(25(38)39)17-10-18(26(28,29)30)12-19(11-17)27(31,32)33/h5-12,23,35H,4,13H2,1-3H3,(H,38,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043464 ((3,5-Bis-trifluoromethyl-phenyl)-[4-(2-ethyl-5,7-d...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C27H24F6N4O2/c1-4-21-36-22-14(2)9-15(3)34-24(22)37(21)13-16-5-7-20(8-6-16)35-23(25(38)39)17-10-18(26(28,29)30)12-19(11-17)27(31,32)33/h5-12,23,35H,4,13H2,1-3H3,(H,38,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair