null

SMILES: CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1

InChI Key: InChIKey=IBOMUNBFESSIAD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50043470 (CHEMBL336738 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C28H32N4O2/c1-5-16-31(26(28(33)34)22-10-8-7-9-11-22)23-14-12-21(13-15-23)18-32-24(6-2)30-25-19(3)17-20(4)29-27(25)32/h7-15,17,26H,5-6,16,18H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043470 (CHEMBL336738 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C28H32N4O2/c1-5-16-31(26(28(33)34)22-10-8-7-9-11-22)23-14-12-21(13-15-23)18-32-24(6-2)30-25-19(3)17-20(4)29-27(25)32/h7-15,17,26H,5-6,16,18H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair