BDBM50043745 CHEMBL47907::{(R)-1-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-butylamino]-propyl}-phosphonic acid

SMILES: CC[C@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC)P(O)(O)=O

InChI Key: InChIKey=UTCZEIUWFUVIQV-YESZJQIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50043745 (CHEMBL47907 | {(R)-1-[(S)-3-Methyl-1-((S)-1-methyl...) Show SMILES CC[C@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC)P(O)(O)=O Show InChI InChI=1S/C19H32N3O5P/c1-5-17(28(25,26)27)21-15(11-13(2)3)19(24)22-16(18(23)20-4)12-14-9-7-6-8-10-14/h6-10,13,15-17,21H,5,11-12H2,1-4H3,(H,20,23)(H,22,24)(H2,25,26,27)/t15-,16-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human fibroblast collagenase				Bioorg Med Chem Lett 4: 2833-2836 (1994) Article DOI: 10.1016/S0960-894X(01)80823-4 BindingDB Entry DOI: 10.7270/Q2HH6K16
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50043745 (CHEMBL47907 | {(R)-1-[(S)-3-Methyl-1-((S)-1-methyl...) Show SMILES CC[C@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC)P(O)(O)=O Show InChI InChI=1S/C19H32N3O5P/c1-5-17(28(25,26)27)21-15(11-13(2)3)19(24)22-16(18(23)20-4)12-14-9-7-6-8-10-14/h6-10,13,15-17,21H,5,11-12H2,1-4H3,(H,20,23)(H,22,24)(H2,25,26,27)/t15-,16-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenase				J Med Chem 37: 158-69 (1994) BindingDB Entry DOI: 10.7270/Q25M64SM
					More data for this Ligand-Target Pair