BDBM50043852 (E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulfonyl)-amino]-ethyl}-phenyl)-6-pyridin-3-yl-hex-5-enoic acid::CHEMBL126196

SMILES: NC(=O)CN(CCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=KEOWJWUNPZAGBC-VVAXDPKNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50043852 ((E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulf...) Show SMILES NC(=O)CN(CCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H28ClN3O5S/c28-23-11-13-24(14-12-23)37(35,36)31(19-26(29)32)17-15-20-7-9-21(10-8-20)25(5-1-2-6-27(33)34)22-4-3-16-30-18-22/h3-5,7-14,16,18H,1-2,6,15,17,19H2,(H2,29,32)(H,33,34)/b25-5+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50043852 ((E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulf...) Show SMILES NC(=O)CN(CCc1ccc(cc1)C(=C/CCCC(O)=O)\c1cccnc1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H28ClN3O5S/c28-23-11-13-24(14-12-23)37(35,36)31(19-26(29)32)17-15-20-7-9-21(10-8-20)25(5-1-2-6-27(33)34)22-4-3-16-30-18-22/h3-5,7-14,16,18H,1-2,6,15,17,19H2,(H2,29,32)(H,33,34)/b25-5+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets.				J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4
					More data for this Ligand-Target Pair