BDBM50043923 CHEMBL3356018

SMILES: Nc1n[nH]c2cc(ccc12)-c1ccc(NS(=O)(=O)c2ccc(Br)s2)cc1

InChI Key: InChIKey=JYACJGJNMOFRNJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043923 (CHEMBL3356018) Show SMILES Nc1n[nH]c2cc(ccc12)-c1ccc(NS(=O)(=O)c2ccc(Br)s2)cc1 Show InChI InChI=1S/C17H13BrN4O2S2/c18-15-7-8-16(25-15)26(23,24)22-12-4-1-10(2-5-12)11-3-6-13-14(9-11)20-21-17(13)19/h1-9,22H,(H3,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...				ACS Med Chem Lett 6: 73-8 (2015) Article DOI: 10.1021/ml5003376 BindingDB Entry DOI: 10.7270/Q28S4RJT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043923 (CHEMBL3356018) Show SMILES Nc1n[nH]c2cc(ccc12)-c1ccc(NS(=O)(=O)c2ccc(Br)s2)cc1 Show InChI InChI=1S/C17H13BrN4O2S2/c18-15-7-8-16(25-15)26(23,24)22-12-4-1-10(2-5-12)11-3-6-13-14(9-11)20-21-17(13)19/h1-9,22H,(H3,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	718	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...				ACS Med Chem Lett 6: 73-8 (2015) Article DOI: 10.1021/ml5003376 BindingDB Entry DOI: 10.7270/Q28S4RJT
					More data for this Ligand-Target Pair