BDBM50043945 CHEMBL91222::N,N'-Bis-(3-methoxy-phenyl)-guanidine

SMILES: COc1cccc(NC(N)=Nc2cccc(OC)c2)c1

InChI Key: InChIKey=HNJBHSJXCZZKKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50043945 (CHEMBL91222 | N,N'-Bis-(3-methoxy-phenyl)-guanidin...) Show SMILES COc1cccc(NC(N)=Nc2cccc(OC)c2)c1 |w:10.10| Show InChI InChI=1S/C15H17N3O2/c1-19-13-7-3-5-11(9-13)17-15(16)18-12-6-4-8-14(10-12)20-2/h3-10H,1-2H3,(H3,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane				J Med Chem 37: 260-7 (1994) BindingDB Entry DOI: 10.7270/Q2HX1BRZ
					More data for this Ligand-Target Pair