BDBM50043962 CHEMBL91828::N'-(2-Isopropyl-phenyl)-N-methyl-N-naphthalen-1-yl-guanidine

SMILES: CC(C)c1ccccc1N=C(N)N(C)c1cccc2ccccc12

InChI Key: InChIKey=MHWCTGIUQCXCOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50043962 (CHEMBL91828 | N'-(2-Isopropyl-phenyl)-N-methyl-N-n...) Show SMILES CC(C)c1ccccc1N=C(N)N(C)c1cccc2ccccc12 |w:9.9| Show InChI InChI=1S/C21H23N3/c1-15(2)17-11-6-7-13-19(17)23-21(22)24(3)20-14-8-10-16-9-4-5-12-18(16)20/h4-15H,1-3H3,(H2,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane				J Med Chem 37: 260-7 (1994) BindingDB Entry DOI: 10.7270/Q2HX1BRZ
					More data for this Ligand-Target Pair