BDBM50043981 CHEMBL88639::N'-(3-Amino-phenyl)-N-methyl-N-naphthalen-1-yl-guanidine

SMILES: CN(C(N)=Nc1cccc(N)c1)c1cccc2ccccc12

InChI Key: InChIKey=JYFLCYPETKPRTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50043981 (CHEMBL88639 | N'-(3-Amino-phenyl)-N-methyl-N-napht...) Show SMILES CN(C(N)=Nc1cccc(N)c1)c1cccc2ccccc12 |w:4.4| Show InChI InChI=1S/C18H18N4/c1-22(18(20)21-15-9-5-8-14(19)12-15)17-11-4-7-13-6-2-3-10-16(13)17/h2-12H,19H2,1H3,(H2,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane				J Med Chem 37: 260-7 (1994) BindingDB Entry DOI: 10.7270/Q2HX1BRZ
					More data for this Ligand-Target Pair