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BDBM50044046 CHEMBL323476::N-[2-(3,4-Dichloro-phenyl)-ethyl]-N,N'-dimethyl-N'-(3-pyrrolidin-1-yl-propyl)-propane-1,3-diamine

SMILES: CN(CCCN(C)CCc1ccc(Cl)c(Cl)c1)CCCN1CCCC1

InChI Key: InChIKey=VQIKUQLDRFQUEC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044046   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50044046
PNG
(CHEMBL323476 | N-[2-(3,4-Dichloro-phenyl)-ethyl]-N...)
Show SMILES CN(CCCN(C)CCc1ccc(Cl)c(Cl)c1)CCCN1CCCC1
Show InChI InChI=1S/C20H33Cl2N3/c1-23(12-6-15-25-13-3-4-14-25)10-5-11-24(2)16-9-18-7-8-19(21)20(22)17-18/h7-8,17H,3-6,9-16H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 78n/an/an/an/an/an/an/an/a



National Institutes of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity towards sigma 1 receptor was determined in guinea pig brain membrane using [3H](+)-pentazocine as radioligand

J Med Chem 37: 314-21 (1994)


BindingDB Entry DOI: 10.7270/Q20C4WFH
More data for this
Ligand-Target Pair