BDBM50044259 CHEMBL3310052

SMILES: Oc1ncnc2c(ccc(Nc3ccc(NC(=O)Nc4ccc(cc4Cl)C(F)(F)F)cc3)c12)[N+]([O-])=O

InChI Key: InChIKey=PVEPKDSVNPUJEX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50044259 (CHEMBL3310052) Show SMILES Oc1ncnc2c(ccc(Nc3ccc(NC(=O)Nc4ccc(cc4Cl)C(F)(F)F)cc3)c12)[N+]([O-])=O Show InChI InChI=1S/C22H14ClF3N6O4/c23-14-9-11(22(24,25)26)1-6-15(14)31-21(34)30-13-4-2-12(3-5-13)29-16-7-8-17(32(35)36)19-18(16)20(33)28-10-27-19/h1-10,29H,(H,27,28,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Eur J Med Chem 76: 193-244 (2014) Article DOI: 10.1016/j.ejmech.2014.02.005 BindingDB Entry DOI: 10.7270/Q26T0P8M
					More data for this Ligand-Target Pair