BDBM50044261 CHEMBL3310054

SMILES: Brc1ccc(Nc2ncnc3ccc(NC(=O)Cc4cccc(Br)c4)cc23)cc1

InChI Key: InChIKey=JIAJFPBNXWZXJU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50044261 (CHEMBL3310054) Show SMILES Brc1ccc(Nc2ncnc3ccc(NC(=O)Cc4cccc(Br)c4)cc23)cc1 Show InChI InChI=1S/C22H16Br2N4O/c23-15-4-6-17(7-5-15)28-22-19-12-18(8-9-20(19)25-13-26-22)27-21(29)11-14-2-1-3-16(24)10-14/h1-10,12-13H,11H2,(H,27,29)(H,25,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University Curated by ChEMBL					Assay Description Inhibition of c-Src (unknown origin)				Eur J Med Chem 76: 193-244 (2014) Article DOI: 10.1016/j.ejmech.2014.02.005 BindingDB Entry DOI: 10.7270/Q26T0P8M
					More data for this Ligand-Target Pair