BDBM50044341 5-Butyl-2-(2-ethoxy-2-phenyl-ethyl)-4-[2'-(2-methyl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL303683

SMILES: CCCCc1nn(CC(OCC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn(C)n1

InChI Key: InChIKey=IBRWLXXIKMQPHY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50044341 (5-Butyl-2-(2-ethoxy-2-phenyl-ethyl)-4-[2'-(2-methy...) Show SMILES CCCCc1nn(CC(OCC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn(C)n1 Show InChI InChI=1S/C31H35N7O2/c1-4-6-16-29-33-38(22-28(40-5-2)25-12-8-7-9-13-25)31(39)37(29)21-23-17-19-24(20-18-23)26-14-10-11-15-27(26)30-32-35-36(3)34-30/h7-15,17-20,28H,4-6,16,21-22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Searle R&D Curated by ChEMBL					Assay Description Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranes				J Med Chem 36: 2172-81 (1993) BindingDB Entry DOI: 10.7270/Q2C53JXM
					More data for this Ligand-Target Pair