null

SMILES: CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=RVAXYBUSVWMATJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50044346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50044346 (5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...				J Med Chem 36: 2558-68 (1993) BindingDB Entry DOI: 10.7270/Q2KP817C
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor B (RAT)	BDBM50044346 (5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Searle R&D Curated by ChEMBL					Assay Description Inhibition of [125I]-angiotensin-II binding to the angiotensin II receptor type 1 in rat uterine membranes				J Med Chem 36: 2172-81 (1993) BindingDB Entry DOI: 10.7270/Q2C53JXM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50044346 (5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.20E+9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albumin				Citation and Details Article DOI: 10.1007/s00044-009-9197-5 BindingDB Entry DOI: 10.7270/Q2H41V9D
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50044346 (5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranes				Citation and Details Article DOI: 10.1007/s00044-011-9622-4 BindingDB Entry DOI: 10.7270/Q2T156HH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50044346 (5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albumin				Citation and Details Article DOI: 10.1007/s00044-009-9197-5 BindingDB Entry DOI: 10.7270/Q2H41V9D
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50044346 (5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in Rattus norvegicus (rat) uterine membranes				Citation and Details Article DOI: 10.1007/s00044-011-9622-4 BindingDB Entry DOI: 10.7270/Q2T156HH
					More data for this Ligand-Target Pair