BDBM50044571 CHEMBL87572

SMILES: CCOC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1C(F)(F)F

InChI Key: InChIKey=KYWQOCQRSFYWPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50044571 (CHEMBL87572) Show SMILES CCOC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1C(F)(F)F |t:13| Show InChI InChI=1S/C13H11F3N4O4/c1-3-24-11(23)7-5-17-12(18-9(7)13(14,15)16)19-20-8(21)4-6(2)10(20)22/h4-5H,3H2,1-2H3,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair