BDBM50044580 CHEMBL3341905

SMILES: FC(F)(F)c1ccc2COCN(C(=O)c3cnc(Cl)nc3C(F)(F)F)c2c1

InChI Key: InChIKey=VLQZZWXDZBWRLG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor Jun (Homo sapiens (Human))	BDBM50044580 (CHEMBL3341905) Show SMILES FC(F)(F)c1ccc2COCN(C(=O)c3cnc(Cl)nc3C(F)(F)F)c2c1 Show InChI InChI=1S/C15H8ClF6N3O2/c16-13-23-4-9(11(24-13)15(20,21)22)12(26)25-6-27-5-7-1-2-8(3-10(7)25)14(17,18)19/h1-4H,5-6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair