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SMILES: Fc1ccc2Oc3c(cccc3C(=O)N(Cc3cccc(c3)C(F)(F)F)c2c1)N1CCNCC1

InChI Key: InChIKey=UKUSBCHEZDGDHS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044594   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50044594
PNG
(CHEMBL3329452)
Show SMILES Fc1ccc2Oc3c(cccc3C(=O)N(Cc3cccc(c3)C(F)(F)F)c2c1)N1CCNCC1
Show InChI InChI=1S/C25H21F4N3O2/c26-18-7-8-22-21(14-18)32(15-16-3-1-4-17(13-16)25(27,28)29)24(33)19-5-2-6-20(23(19)34-22)31-11-9-30-10-12-31/h1-8,13-14,30H,9-12,15H2
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Article
PubMed
 0.300n/an/an/an/an/an/an/an/a



Universidad Complutense de Madrid

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells

J Med Chem 57: 7160-81 (2014)


Article DOI: 10.1021/jm5003952
BindingDB Entry DOI: 10.7270/Q2X92CZZ
More data for this
Ligand-Target Pair