BDBM50044644 CHEMBL3311472

SMILES: ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1

InChI Key: InChIKey=ITSLNGBJYKFUFZ-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 2 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50044644 (CHEMBL3311472) Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C17H23N3O4/c21-15-9-7-12-11-13(6-8-14(12)19-15)17(23)18-10-4-2-1-3-5-16(22)20-24/h6,8,11,24H,1-5,7,9-10H2,(H,18,23)(H,19,21)(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Pharmaceutical Chemicals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assay				Bioorg Med Chem 22: 3720-31 (2014) Article DOI: 10.1016/j.bmc.2014.05.001 BindingDB Entry DOI: 10.7270/Q24T6M0V
					More data for this Ligand-Target Pair