BDBM50044887 8-Chloro-10b-methyl-1,4,6,10b-tetrahydro-2H-benzo[f]quinolin-3-one::CHEMBL134819

SMILES: CC12CCC(=O)NC1=CCc1cc(Cl)ccc21

InChI Key: InChIKey=VAIZKBFWLGGIEL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50044887 (8-Chloro-10b-methyl-1,4,6,10b-tetrahydro-2H-benzo[...) Show SMILES CC12CCC(=O)NC1=CCc1cc(Cl)ccc21 |c:8| Show InChI InChI=1S/C14H14ClNO/c1-14-7-6-13(17)16-12(14)5-2-9-8-10(15)3-4-11(9)14/h3-5,8H,2,6-7H2,1H3,(H,16,17)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of DHT production in Hs 68 (human genital fibroblast) cells.				J Med Chem 36: 421-3 (1993) BindingDB Entry DOI: 10.7270/Q2T43TQX
					More data for this Ligand-Target Pair