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SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cccc(F)c5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=UJWCNUHITLVMJO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044956   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50044956
PNG
(CHEMBL3309403)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cccc(F)c5)c(=O)c5ccccc45)cc3F)ccnc2cc1OCCCN1CCCC1
Show InChI InChI=1S/C38H33F2N5O5/c1-48-34-22-29-31(23-35(34)49-19-7-18-44-16-4-5-17-44)41-15-14-32(29)50-33-13-12-25(21-30(33)40)42-37(46)36-27-10-2-3-11-28(27)38(47)45(43-36)26-9-6-8-24(39)20-26/h2-3,6,8-15,20-23H,4-5,7,16-19H2,1H3,(H,42,46)
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Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) after 30 mins using poly (Glu,Tyr)4:1 substrate

Bioorg Med Chem 22: 3642-53 (2014)


Article DOI: 10.1016/j.bmc.2014.05.013
BindingDB Entry DOI: 10.7270/Q23T9JV2
More data for this
Ligand-Target Pair