BDBM50044987 (O10eq)-beta-N,N'-Bis-Benzyloxycarbonyl-guanidinopropionylryanodine::CHEMBL27869

SMILES: CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCNC(NC(=O)OCc6ccccc6)=NC(=O)OCc6ccccc6)C(C)CCC35O)C2(O)C14C

InChI Key: InChIKey=OODCQSZBEABRLE-RHMKQUNFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ryanodine receptor 1 (Oryctolagus cuniculus)	BDBM50044987 ((O10eq)-beta-N,N'-Bis-Benzyloxycarbonyl-guanidinop...) Show SMILES CC(C)C1(O)[C@@H](OC(=O)c2ccc[nH]2)C2(O)[C@@]3(C)CC4(O)OC5([C@H](OC(=O)CCNC(NC(=O)OCc6ccccc6)=NC(=O)OCc6ccccc6)C(C)CCC35O)C2(O)C14C |w:42.44,TLB:57:16:61:22.21,3:61:22.21:14.16.18,60:59:3.5:16.19.18,15:14:22.57:61.19.18,15:14:61:22.21,6:5:59:16.19.18,20:19:59:3.5,THB:22:59:3.5:16.19.18,57:22:61:14.16.18,57:16:59:3.5,4:3:59:16.19.18,5:14:22.57:61.19.18,5:14:61:22.21,21:19:59:3.5,23:22:61:14.16.18,62:61:22.21:14.16.18| Show InChI InChI=1S/C45H54N4O14/c1-26(2)42(56)34(62-33(51)30-17-12-21-46-30)43(57)38(4)25-41(55)39(42,5)45(43,58)44(63-41)32(27(3)18-20-40(38,44)54)61-31(50)19-22-47-35(48-36(52)59-23-28-13-8-6-9-14-28)49-37(53)60-24-29-15-10-7-11-16-29/h6-17,21,26-27,32,34,46,54-58H,18-20,22-25H2,1-5H3,(H2,47,48,49,52,53)/t27?,32-,34-,38+,39?,40?,41?,42?,43?,44?,45?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University Curated by ChEMBL					Assay Description Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesicles				J Med Chem 36: 1319-23 (1993) BindingDB Entry DOI: 10.7270/Q2PN968V
					More data for this Ligand-Target Pair