BDBM50045009 2-(2-Hexyloxy-phenyl)-3H-imidazo[4,5-b]pyridine::CHEMBL28566

SMILES: CCCCCCOc1ccccc1-c1nc2ncccc2[nH]1

InChI Key: InChIKey=ZQDVZUHICYDCIR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50045009 (2-(2-Hexyloxy-phenyl)-3H-imidazo[4,5-b]pyridine | ...) Show SMILES CCCCCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C18H21N3O/c1-2-3-4-7-13-22-16-11-6-5-9-14(16)17-20-15-10-8-12-19-18(15)21-17/h5-6,8-12H,2-4,7,13H2,1H3,(H,19,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-IV isolated from guinea pig ventricle.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50045009 (2-(2-Hexyloxy-phenyl)-3H-imidazo[4,5-b]pyridine | ...) Show SMILES CCCCCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C18H21N3O/c1-2-3-4-7-13-22-16-11-6-5-9-14(16)17-20-15-10-8-12-19-18(15)21-17/h5-6,8-12H,2-4,7,13H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-V isolated from porcine pulmonary artery.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair