BDBM50045011 3-[2-(3H-Imidazo[4,5-b]pyridin-2-yl)-phenoxy]-propan-1-ol::CHEMBL281663

SMILES: OCCCOc1ccccc1-c1nc2ncccc2[nH]1

InChI Key: InChIKey=GTISORQHPBRGPY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50045011 (3-[2-(3H-Imidazo[4,5-b]pyridin-2-yl)-phenoxy]-prop...) Show SMILES OCCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C15H15N3O2/c19-9-4-10-20-13-7-2-1-5-11(13)14-17-12-6-3-8-16-15(12)18-14/h1-3,5-8,19H,4,9-10H2,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-V isolated from porcine pulmonary artery.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair