BDBM50045014 2-(2-Cyclopropylmethoxy-phenyl)-3H-imidazo[4,5-b]pyridine::CHEMBL28835

SMILES: C(Oc1ccccc1-c1nc2ncccc2[nH]1)C1CC1

InChI Key: InChIKey=LWYSMGJJCIJHGK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50045014 (2-(2-Cyclopropylmethoxy-phenyl)-3H-imidazo[4,5-b]p...) Show SMILES C(Oc1ccccc1-c1nc2ncccc2[nH]1)C1CC1 Show InChI InChI=1S/C16H15N3O/c1-2-6-14(20-10-11-7-8-11)12(4-1)15-18-13-5-3-9-17-16(13)19-15/h1-6,9,11H,7-8,10H2,(H,17,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-IV isolated from guinea pig ventricle.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50045014 (2-(2-Cyclopropylmethoxy-phenyl)-3H-imidazo[4,5-b]p...) Show SMILES C(Oc1ccccc1-c1nc2ncccc2[nH]1)C1CC1 Show InChI InChI=1S/C16H15N3O/c1-2-6-14(20-10-11-7-8-11)12(4-1)15-18-13-5-3-9-17-16(13)19-15/h1-6,9,11H,7-8,10H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-V isolated from porcine pulmonary artery.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair