BDBM50045017 2-[2-(3-Chloro-propoxy)-phenyl]-3H-imidazo[4,5-b]pyridine::CHEMBL280830

SMILES: ClCCCOc1ccccc1-c1nc2ncccc2[nH]1

InChI Key: InChIKey=UJRNYHKHPUWWMJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50045017 (2-[2-(3-Chloro-propoxy)-phenyl]-3H-imidazo[4,5-b]p...) Show SMILES ClCCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C15H14ClN3O/c16-8-4-10-20-13-7-2-1-5-11(13)14-18-12-6-3-9-17-15(12)19-14/h1-3,5-7,9H,4,8,10H2,(H,17,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-IV isolated from guinea pig ventricle.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50045017 (2-[2-(3-Chloro-propoxy)-phenyl]-3H-imidazo[4,5-b]p...) Show SMILES ClCCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C15H14ClN3O/c16-8-4-10-20-13-7-2-1-5-11(13)14-18-12-6-3-9-17-15(12)19-14/h1-3,5-7,9H,4,8,10H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-V isolated from porcine pulmonary artery.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair