BDBM50045023 Acetic acid 2-(3H-imidazo[4,5-b]pyridin-2-yl)-phenyl ester::CHEMBL28240

SMILES: CC(=O)Oc1ccccc1-c1nc2ncccc2[nH]1

InChI Key: InChIKey=BUOUYIWCRIZRLZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50045023 (Acetic acid 2-(3H-imidazo[4,5-b]pyridin-2-yl)-phen...) Show SMILES CC(=O)Oc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C14H11N3O2/c1-9(18)19-12-7-3-2-5-10(12)13-16-11-6-4-8-15-14(11)17-13/h2-8H,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-V isolated from porcine pulmonary artery.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair