BDBM50045275 2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-biphenyl-4-carboxylic acid::CHEMBL89253
SMILES: CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccccc1-c1ccc(cc1)C(O)=O
InChI Key: InChIKey=KAGVSHRIUMYRQG-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50045275 (2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphtha...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Effective concentration against RXR-alpha receptor | J Med Chem 36: 2605-13 (1993) BindingDB Entry DOI: 10.7270/Q21R6PKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor beta (Homo sapiens (Human)) | BDBM50045275 (2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphtha...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Effective concentration against Retinoic acid receptor beta | J Med Chem 36: 2605-13 (1993) BindingDB Entry DOI: 10.7270/Q21R6PKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor gamma (Homo sapiens (Human)) | BDBM50045275 (2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphtha...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Effective concentration against RAR-gamma receptor | J Med Chem 36: 2605-13 (1993) BindingDB Entry DOI: 10.7270/Q21R6PKP | |||||||||||
More data for this Ligand-Target Pair |