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SMILES: O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1

InChI Key: InChIKey=PVFUEKFIIVMPFJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50045875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (RAT)	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rattus norvegicus (rat)-RAT)	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibition of [3H]naxolone binding to opiate receptors in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rattus norvegicus (rat)-RAT)	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat))	BDBM50045875 (2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...) Show SMILES O=C1Cc2c([nH]c3cccc(N1)c23)-c1ccccc1 Show InChI InChI=1S/C16H12N2O/c19-14-9-11-15-12(17-14)7-4-8-13(15)18-16(11)10-5-2-1-3-6-10/h1-8,18H,9H2,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brain				J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV
					More data for this Ligand-Target Pair