BDBM50046057 CHEMBL3310276

SMILES: Cc1ccccc1CC(=O)Nc1onc(c1-c1ccncn1)-c1ccc(F)c(C)c1

InChI Key: InChIKey=KGNQMDNYLTXCIM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50046057 (CHEMBL3310276) Show SMILES Cc1ccccc1CC(=O)Nc1onc(c1-c1ccncn1)-c1ccc(F)c(C)c1 Show InChI InChI=1S/C23H19FN4O2/c1-14-5-3-4-6-16(14)12-20(29)27-23-21(19-9-10-25-13-26-19)22(28-30-23)17-7-8-18(24)15(2)11-17/h3-11,13H,12H2,1-2H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
ASKA Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of full length human p38alpha MAP kinase by Off-chip mobility shift assay				Bioorg Med Chem 22: 4162-76 (2014) Article DOI: 10.1016/j.bmc.2014.05.045 BindingDB Entry DOI: 10.7270/Q2C82BXS
					More data for this Ligand-Target Pair