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SMILES: Nc1nc2nc(NCc3cccs3)[nH]c2c(=O)[nH]1

InChI Key: InChIKey=ASPRVQARSFBOHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046246   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purine nucleoside phosphorylase


(Homo sapiens (Human))		BDBM50046246
PNG
(2-Amino-8-[(thiophen-2-ylmethyl)-amino]-1,9-dihydr...)
Show SMILES Nc1nc2nc(NCc3cccs3)[nH]c2c(=O)[nH]1
Show InChI InChI=1S/C10H10N6OS/c11-9-14-7-6(8(17)16-9)13-10(15-7)12-4-5-2-1-3-18-5/h1-3H,4H2,(H5,11,12,13,14,15,16,17)
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PubMed
n/an/a 0.160n/an/an/an/an/an/a



BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphate

J Med Chem 36: 55-69 (1993)


BindingDB Entry DOI: 10.7270/Q2B27TCX
More data for this
Ligand-Target Pair