BDBM50046357 1-(1,2,3,4-Tetrahydro-quinoline-2-carbonyl)-pyrrolidine-2-carboxylic acid (1-formyl-4-guanidino-butyl)-amide::CHEMBL2370422

SMILES: NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCc2ccccc2N1)C=O

InChI Key: InChIKey=LFIGHRNZFXNOEV-YKOWGRMDSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50046357 (1-(1,2,3,4-Tetrahydro-quinoline-2-carbonyl)-pyrrol...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCc2ccccc2N1)C=O Show InChI InChI=1S/C21H30N6O3/c22-21(23)24-11-3-6-15(13-28)25-19(29)18-8-4-12-27(18)20(30)17-10-9-14-5-1-2-7-16(14)26-17/h1-2,5,7,13,15,17-18,26H,3-4,6,8-12H2,(H,25,29)(H4,22,23,24)/t15-,17?,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against plasmin				J Med Chem 36: 314-9 (1993) BindingDB Entry DOI: 10.7270/Q2930S8J
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50046357 (1-(1,2,3,4-Tetrahydro-quinoline-2-carbonyl)-pyrrol...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCc2ccccc2N1)C=O Show InChI InChI=1S/C21H30N6O3/c22-21(23)24-11-3-6-15(13-28)25-19(29)18-8-4-12-27(18)20(30)17-10-9-14-5-1-2-7-16(14)26-17/h1-2,5,7,13,15,17-18,26H,3-4,6,8-12H2,(H,25,29)(H4,22,23,24)/t15-,17?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against thrombin				J Med Chem 36: 314-9 (1993) BindingDB Entry DOI: 10.7270/Q2930S8J
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50046357 (1-(1,2,3,4-Tetrahydro-quinoline-2-carbonyl)-pyrrol...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCc2ccccc2N1)C=O Show InChI InChI=1S/C21H30N6O3/c22-21(23)24-11-3-6-15(13-28)25-19(29)18-8-4-12-27(18)20(30)17-10-9-14-5-1-2-7-16(14)26-17/h1-2,5,7,13,15,17-18,26H,3-4,6,8-12H2,(H,25,29)(H4,22,23,24)/t15-,17?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against trypsin				J Med Chem 36: 314-9 (1993) BindingDB Entry DOI: 10.7270/Q2930S8J
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50046357 (1-(1,2,3,4-Tetrahydro-quinoline-2-carbonyl)-pyrrol...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCc2ccccc2N1)C=O Show InChI InChI=1S/C21H30N6O3/c22-21(23)24-11-3-6-15(13-28)25-19(29)18-8-4-12-27(18)20(30)17-10-9-14-5-1-2-7-16(14)26-17/h1-2,5,7,13,15,17-18,26H,3-4,6,8-12H2,(H,25,29)(H4,22,23,24)/t15-,17?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against factor Xa				J Med Chem 36: 314-9 (1993) BindingDB Entry DOI: 10.7270/Q2930S8J
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50046357 (1-(1,2,3,4-Tetrahydro-quinoline-2-carbonyl)-pyrrol...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1CCc2ccccc2N1)C=O Show InChI InChI=1S/C21H30N6O3/c22-21(23)24-11-3-6-15(13-28)25-19(29)18-8-4-12-27(18)20(30)17-10-9-14-5-1-2-7-16(14)26-17/h1-2,5,7,13,15,17-18,26H,3-4,6,8-12H2,(H,25,29)(H4,22,23,24)/t15-,17?,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against plasmin				J Med Chem 36: 314-9 (1993) BindingDB Entry DOI: 10.7270/Q2930S8J
					More data for this Ligand-Target Pair