BDBM50046573 CHEMBL3309973

SMILES: COc1cc(=O)n(cc1C(=O)NCc1ccc(F)cc1)-c1ccc(Oc2ccnc(N)c2-c2ccc(F)cc2)c(F)c1

InChI Key: InChIKey=JQGNMEXDNVFIAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50046573 (CHEMBL3309973) Show SMILES COc1cc(=O)n(cc1C(=O)NCc1ccc(F)cc1)-c1ccc(Oc2ccnc(N)c2-c2ccc(F)cc2)c(F)c1 Show InChI InChI=1S/C31H23F3N4O4/c1-41-27-15-28(39)38(17-23(27)31(40)37-16-18-2-6-20(32)7-3-18)22-10-11-25(24(34)14-22)42-26-12-13-36-30(35)29(26)19-4-8-21(33)9-5-19/h2-15,17H,16H2,1H3,(H2,35,36)(H,37,40)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of recombinant MET kinase domain (unknown origin)				Bioorg Med Chem Lett 24: 3351-5 (2014) Article DOI: 10.1016/j.bmcl.2014.05.097 BindingDB Entry DOI: 10.7270/Q2JS9S2B
					More data for this Ligand-Target Pair