BindingDB PrimarySearch

BDBM50046894 2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-pentanoic acid (1-formyl-4-guanidino-butyl)-amide::CHEMBL2373062

SMILES: [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](-[#6])=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6]=O

InChI Key: InChIKey=VTOGQBLCPOHMEG-JYJNAYRXSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046894
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cathepsin B (Bos taurus (bovine))	BDBM50046894 (2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas Curated by ChEMBL					Assay Description Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrate				J Med Chem 36: 1084-9 (1993) BindingDB Entry DOI: 10.7270/Q24F1RCR
University of Arkansas Curated by ChEMBL					More data for this Ligand-Target Pair
Thrombin (Bos taurus (Bovine))	BDBM50046894 (2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas Curated by ChEMBL					Assay Description Inhibition of thrombin with benzoyl-Phe-Val-arginine- p-nitroanilide as substrate				J Med Chem 36: 1084-9 (1993) BindingDB Entry DOI: 10.7270/Q24F1RCR
University of Arkansas Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen (Bos taurus)	BDBM50046894 (2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas Curated by ChEMBL					Assay Description Inhibition of plasmin with Val-L-Leu-L-lysine-p-nitroanilide as substrate				J Med Chem 36: 1084-9 (1993) BindingDB Entry DOI: 10.7270/Q24F1RCR
University of Arkansas Curated by ChEMBL					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM50046894 (2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas Curated by ChEMBL					Assay Description Inhibition of kallikrein with benzoyl-L-arginine ethyl ester as substrate				J Med Chem 36: 1084-9 (1993) BindingDB Entry DOI: 10.7270/Q24F1RCR
University of Arkansas Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50046894 (2-(2-Acetylamino-3-methyl-butyrylamino)-4-methyl-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas Curated by ChEMBL					Assay Description Inhibition of trypsin with benzoyl-L-arginine ethyl ester as substrate				J Med Chem 36: 1084-9 (1993) BindingDB Entry DOI: 10.7270/Q24F1RCR
University of Arkansas Curated by ChEMBL					More data for this Ligand-Target Pair