BDBM50046908 5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL12234
SMILES: CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1n[nH]c(=O)[nH]1
InChI Key: InChIKey=RATUQWLTDDJCRS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50046908 (5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-2,4-dihydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cells | J Med Chem 36: 1090-9 (1993) BindingDB Entry DOI: 10.7270/Q20P10PV | |||||||||||
More data for this Ligand-Target Pair |