BDBM50047077 4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-yl]-3,3-dimethyl-butyric acid::CHEMBL277826

SMILES: CC(C)(CC(O)=O)Cc1nc2ccccc2n1Cc1ccc(Cl)cc1

InChI Key: InChIKey=CMHWPXSZUPSRNR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50047077 (4-[1-(4-Chloro-benzyl)-1H-benzoimidazol-2-yl]-3,3-...) Show SMILES CC(C)(CC(O)=O)Cc1nc2ccccc2n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN2O2/c1-20(2,12-19(24)25)11-18-22-16-5-3-4-6-17(16)23(18)13-14-7-9-15(21)10-8-14/h3-10H,11-13H2,1-2H3,(H,24,25)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Carpibem Curated by ChEMBL					Assay Description Tested in vitro for inhibition constant against TXA2 / PGH-2 receptor using [125I]-PTA-OH binding affinity to human platelets				J Med Chem 36: 1175-87 (1993) BindingDB Entry DOI: 10.7270/Q2R49PT8
					More data for this Ligand-Target Pair