BDBM50047534 1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propoxy]-6-methyl-phenyl}-3-(3-methyl-butyl)-urea::CHEMBL42296

SMILES: CC(C)CCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1

InChI Key: InChIKey=SMTLYJABEMNOOF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047534 (1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propo...) Show SMILES CC(C)CCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1 Show InChI InChI=1S/C28H38N4O2/c1-20(2)15-16-29-28(33)31-25-22(5)11-9-14-24(25)34-18-10-17-32-19-30-26(27(32)21(3)4)23-12-7-6-8-13-23/h6-9,11-14,19-21H,10,15-18H2,1-5H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047534 (1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propo...) Show SMILES CC(C)CCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1 Show InChI InChI=1S/C28H38N4O2/c1-20(2)15-16-29-28(33)31-25-22(5)11-9-14-24(25)34-18-10-17-32-19-30-26(27(32)21(3)4)23-12-7-6-8-13-23/h6-9,11-14,19-21H,10,15-18H2,1-5H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair