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BDBM50047881 4-Hydroxy-7-methyl-[1,8]naphthyridine-3-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::CHEMBL435232

SMILES: CN1C2CCC1CC(C2)OC(=O)c1cnc2nc(C)ccc2c1O

InChI Key: InChIKey=WMURKFAEZXXMDJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047881   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50047881
PNG
(4-Hydroxy-7-methyl-[1,8]naphthyridine-3-carboxylic...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)c1cnc2nc(C)ccc2c1O |THB:9:7:1:3.4|
Show InChI InChI=1S/C18H21N3O3/c1-10-3-6-14-16(22)15(9-19-17(14)20-10)18(23)24-13-7-11-4-5-12(8-13)21(11)2/h3,6,9,11-13H,4-5,7-8H2,1-2H3,(H,19,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
>100n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.

J Med Chem 36: 617-26 (1993)


BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair