BDBM50047882 4-Hydroxy-7-methyl-[1,8]naphthyridine-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::CHEMBL155819

SMILES: CN1C2CCC1CC(C2)NC(=O)c1cnc2nc(C)ccc2c1O

InChI Key: InChIKey=NPHCETPQOTYHCU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50047882 (4-Hydroxy-7-methyl-[1,8]naphthyridine-3-carboxylic...) Show SMILES CN1C2CCC1CC(C2)NC(=O)c1cnc2nc(C)ccc2c1O |THB:9:7:1:3.4| Show InChI InChI=1S/C18H22N4O2/c1-10-3-6-14-16(23)15(9-19-17(14)20-10)18(24)21-11-7-12-4-5-13(8-11)22(12)2/h3,6,9,11-13H,4-5,7-8H2,1-2H3,(H,21,24)(H,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.				J Med Chem 36: 617-26 (1993) BindingDB Entry DOI: 10.7270/Q25B034N
					More data for this Ligand-Target Pair